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SAM-e is an active lipotrope form of Methionine. SAMe is manufactured within the body but it is made synthetically. SAMe is a cofactor in a number of critical biochemical reactions and is found in almost every tissue of the body. SAMe has been used in clinical studies to treat depression, schizophrenia, demyelination diseases, liver disease, dementia, arthritis, peripheral neuropathy and other conditions.
SAMe alleviates all forms of depression. Several studies have confirmed that SAMe is up to15% more effective in the treatment of depression than traditional pharmaceutical anti-depressants.
SAMe improves and normalizes liver function. SAMe is used in Europe in the treatment of cirrhosis and damage caused by alcohol. SAMe is essential for the production of glutathione, a powerful antioxidant that protects the body from the damaging effects of free radicals.
SAMe reduces the number of trigger points, reduces fatigue, reduces morning stiffness and improves mood in fibromyalgia patients.
SAMe improves the binding of neurotransmitters to their receptors sites in the brain. SAMe is essential for the regeneration of neuron axons following injury. SAMe is essential for the formation of myelin sheaths that surround axons. In tests SAMe has shown great promise in the treatment of Peripheral Neuropathy and HIV related peripheral Neuropathy. Alzheimer's and Parkinson's patients have very low levels of SAMe. SAMe is currently under investigation as a treatment for Parkinson's disease.
SAMe is used during detoxification of drug dependent patients to counteract anxiety and depression.
SAMe has shown great promise in the treatment of peripheral Neuropathy and HIV related peripheral Neuropathy.
Osteoarthritis (OA) affected joints have limitation of movement, loss of dexterity and increasing pain. Affected joints are not visibly inflamed, may be swelling in the finger joints. Research shows that SAM-e improves mobility and relieves pain and helps rebuild damaged cartilage. A study of SAM-e of patients with OA of the knee, hip and spine.
CAUTION: Those suffering from Manic Depression should not take SAMe as SAMe's antidepressant properties may heighten the manic phase.
Because SAM-e is absorbed mainly through the intestine, it's best to take "enteric coated" tablets that pass through the stomach intact or on an empty stomach
Adequate intake of folic acid and vitamin B12 are recommended,
SAM-e (enteric coated) (30 tabs)